Successful treatment with tacrolimus of refractory pyoderma gangrenosum with pouchitis after restorative proctocolectomy for ulcerative colitis
نویسندگان
چکیده
منابع مشابه
Infliximab for treatment of pyoderma gangrenosum with ulcerative colitis.
The recent case report published in the JCC on using combined infliximab and surgery in treatment of pyoderma gangrenosum with ulcerative colitis is interesting.1Andrisani et al. proposed for the effectiveness of this regimen.1The possibility of adverse events on the other side on using infliximab should also be mentioned. The practitioner has to weigh between the usefulness and possible advers...
متن کاملSmoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis.
Epidemiological studies have shown an increased risk of ulcerative colitis (UC) in non-smokers and particularly recent ex-smokers. Patients with UC have an increased risk of pouchitis following ileal pouch-anal anastomosis, which may be a manifestation of the original disease susceptibility. The aim of this study was to test the hypothesis that smoking habit may influence the incidence of pouch...
متن کاملPyoderma gangrenosum associated with ulcerative colitis.
We report the case of a 45-year old man with non-healing ulcers located on his chest, lumbal, sacral, retroauricular areas and forehead. Both clinical and histopathological examinations suggested pyoderma gangrenosum (PG). For six months the diagnosis of ulcerative colitis was established. PG in our patient was presented as a rapidly enlarging, painful ulcer with purple, undermined edges and a ...
متن کاملGeneralized Pyoderma Gangrenosum Associated with Ulcerative Colitis: Successful Treatment with Infliximab and Azathioprine.
Pyoderma gangrenosum (PG) is a rare ulcerative skin disease, part of the spectrum of neutrophilic and auto-inflammatory dermatoses. Its pathogenesis is unknown, although immune pathways have been implicated. Lesion biopsies show a predominantly neutrophilic infiltrate. The incidence of PG is uncertain, but it is estimated to be 3-10 per million per year, occurring at any age but most commonly b...
متن کاملPyoderma gangrenosum and ulcerative colitis.
The relationship of pyoderma gangrenosum and ulcerative colitis remains uncertain. We investigating 14 patients with pyoderma gangrenosum by colonoscopy with multiple biopsies. Six patients had ulcerative colitis and all of these had disease affecting the whole colon. There were no correlations between exacerbations of the colitis and the onset or course of pyoderma gangrenosum. The remaining e...
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ژورنال
عنوان ژورنال: Immunological Medicine
سال: 2018
ISSN: 2578-5826
DOI: 10.1080/25785826.2018.1531194